Dactolisib Tosylate
Dactolisib Tosylate (BEZ235 Tosylate) is a potent dual inhibitor of PI3K and mTOR, with low nanomolar IC50 values against all PI3K isoforms and both mTOR complexes. It is widely used in preclinical research to investigate oncogenic signaling pathways and has demonstrated antitumor activity in various in vitro and in vivo cancer models.
Product Specifications
CAS Number
1028385-32-1
Product Name Alternative
Dactolisib Tosylate, BEZ 235 Tosylate, BEZ235 Tosylate, BEZ-235 Tosylate, Autophagy, mTORC1, mTORC2, mTOR, NVP-BEZ 235 Tosylate, NVP-BEZ235 Tosylate, NVP-BEZ-235 Tosylate, p110β, p110δ, p110γ, p110α, p110α-H1047R, p110α-E545K, PI3K
Field of Research
Cell Biology, Signal Transduction
Purity
99.85% (May vary between batches)
Solubility
H2O:0.1 mg/mL (0.16 mM) ; DMSO:30.6 mg/mL (47.68 mM) ;10% DMSO+90% Corn Oil:1 mg/mL (1.56 mM)
Smiles
Cc1ccc (cc1) S (O) (=O) =O.Cn1c2cnc3ccc (cc3c2n (-c2ccc (cc2) C (C) (C) C#N) c1=O) -c1cnc2ccccc2c1
Molecular Formula
C37H31N5O4S
Molecular Weight
641.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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