BI605906
BI605906 is a selective IKKβ inhibitor that blocks TNF-α-induced IκB degradation and subsequent IL-6 production. This mechanism supports its application in studying NF-κB-driven inflammatory pathways, with research utility in both cellular models and animal studies of conditions like psoriasis.
Product Specifications
CAS Number
960293-88-3
Product Name Alternative
BI605906, BI-605906, BI 605906, at 0.1 mM ATP, IKK, IkB/IKK, IkB, IκB, ILReceptor, IL-6, IKKβ, IL Receptor
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
97.14% (May vary between batches)
Solubility
DMSO:40 mg/mL (92.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.31 mM)
Smiles
CCC (F) (F) c1cc (nc2sc (C (N) =O) c (N) c12) N1CCC (CC1) S (C) (=O) =O
Molecular Formula
C17H22F2N4O3S2
Molecular Weight
432.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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