BIP-135
BIP-135 is a potent, ATP-competitive inhibitor selective for GSK-3α and GSK-3β, with IC50 values of 16 nM and 21 nM, respectively. It demonstrates neuroprotective properties and is a valuable research tool for studying glycogen synthase kinase-3 in both cellular and animal models of neurological function and disease.
Product Specifications
CAS Number
941575-71-9
Product Name Alternative
BIP 135, BIP135, BIP-135, GSK-3β, GSK-3α, GSK3
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
99.77% (May vary between batches)
Solubility
DMSO:56.7 mg/mL (134.6 mM)
Smiles
Cn1cc (C2=C (C (=O) NC2=O) c2coc3ccccc23) c2cc (Br) ccc12
Molecular Formula
C21H13BrN2O3
Molecular Weight
421.24
Storage Conditions
-20°C
Notes
For research use only.
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