BI 689648
BI 689648 is a potent and selective small molecule inhibitor of aldosterone synthase, demonstrating high selectivity for CYP11B2 (IC50 = 2.1 nM) over CYP11B1 (IC50 = 310 nM) . It is a valuable research tool for investigating the renin-angiotensin-aldosterone system in both in vitro enzymatic assays and in vivo models of hypertension and heart failure.
Product Specifications
CAS Number
1633009-87-6
Field of Research
Metabolism Research
Smiles
COCc1cncc (c1) -c1cnc2N (CCCc2c1) C (N) =O
Molecular Formula
C16H18N4O2
Molecular Weight
298.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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