BMS-906024
BMS-906024 (Osugacestat) is a potent, orally bioavailable γ-secretase inhibitor that blocks signaling from all four Notch receptors (Notch1-4) . It demonstrates broad-spectrum antitumor activity in human cancer xenograft models, supporting its investigation in oncology research for both in vitro and in vivo studies.
Product Specifications
CAS Number
1401066-79-2
Product Name Alternative
Osugacestat, Notch2, Notch4, Notch3, Notch, Notch1, Gammasecretase, AL-101, BMS 906024, BMS906024, BMS-906024, BM-0018, γ secretase
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
99.87% (May vary between batches)
Solubility
DMSO:5 mg/mL (8.98 mM)
Smiles
CN1c2ccccc2C (=N[C@H] (NC (=O) [C@H] (CCC (F) (F) F) [C@H] (CCC (F) (F) F) C (N) =O) C1=O) c1ccccc1
Molecular Formula
C26H26F6N4O3
Molecular Weight
556.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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