BMS-935177
BMS-935177 is a potent and reversible inhibitor of Bruton's tyrosine kinase (BTK), exhibiting an IC50 of 3 nM. This small molecule is utilized in biochemical and cellular research to investigate BTK-dependent signaling pathways in immunological and oncological contexts, both in vitro and in vivo.
Product Specifications
CAS Number
1231889-53-4
Product Name Alternative
BMS935177, BMS-935177, BMS 935177, BTK
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.57 mM) ; DMSO:117 mg/mL (232.81 mM)
Smiles
Cc1c (cccc1-n1cnc2ccccc2c1=O) -c1ccc (C (N) =O) c2[nH]c3cc (ccc3c12) C (C) (C) O
Molecular Formula
C31H26N4O3
Molecular Weight
502.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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