BMS CCR2 22
BMS CCR2 22 is a potent, selective CCR2 antagonist, demonstrating high affinity with a binding IC50 of 5.1 nM and functional inhibition of calcium flux (IC50=18 nM) and monocyte chemotaxis (IC50=1 nM) . This compound is a valuable research tool for investigating CCR2-mediated pathways in inflammatory and autoimmune diseases, applicable in both cellular and animal models.
Product Specifications
CAS Number
445479-97-0
Product Name Alternative
BMS CCR2 22, BMS CCR-2 22, CCR2
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (5.56 mM) ; DMSO:225 mg/mL (379 mM)
Smiles
CSc1ccc (cc1) C (=O) N[C@@H]1CCCC[C@@H]1NC (=O) CNC (=O) c1cc (ccc1NC (=O) NC (C) C) C (F) (F) F
Molecular Formula
C28H34F3N5O4S
Molecular Weight
593.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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