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BRD9185

BRD9185 is a potent small molecule inhibitor of Dihydroorotate dehydrogenase (DHODH), demonstrating an EC50 of 16 nM against multidrug-resistant Plasmodium falciparum in vitro. It serves as a valuable chemical probe for studying malaria parasite biology and for antimalarial drug discovery research.

Product Specifications

CAS Number

2057420-29-6

Field of Research

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Smiles

C (#N) [C@@H]1[C@@H] ([C@@H] (CO) N1C (NCCC) =O) C2=CC=C (C=C2) C3=CC (C (F) (F) F) =C (C (F) (F) F) C=C3

Molecular Formula

C23H21F6N3O2

Molecular Weight

485.42

Storage Conditions

-20°C

Notes

For research use only.

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