Bz 423
Bz-423 is a potent immunomodulatory small molecule that induces apoptosis via Bax/Bak activation, leading to mitochondrial outer membrane permeabilization and cytochrome c release. It has demonstrated partial efficacy in a murine lupus model, supporting its research use in studying autoimmune diseases and mitochondrial apoptosis pathways.
Product Specifications
CAS Number
216691-95-1
Product Name Alternative
Bz 423, BZ 48, BZ48, BZ-48, Bax, Bak, Apoptosis
Field of Research
Cell Biology
Purity
98.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.48 mM) ; DMSO:80 mg/mL (181.44 mM)
Smiles
CN1c2ccc (Cl) cc2C (=NC (Cc2ccc3ccccc3c2) C1=O) c1ccc (O) cc1
Molecular Formula
C27H21ClN2O2
Molecular Weight
440.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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