BI 639667
BI 639667 is a potent and selective azaindazole-based CCR1 inhibitor, exhibiting an IC50 of 1.8 nM in calcium mobilization assays. This small molecule is a valuable research tool for investigating CCR1-mediated pathways in inflammatory and autoimmune diseases, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1295298-26-8
Product Name Alternative
CCR1 antagonist 8, CCR1, CCR-1 antagonist 8, CCR1 antagonist8, BI639667
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.86% (May vary between batches)
Solubility
DMSO:8 mg/mL (17.72 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.11 mM)
Smiles
O=C (NC1 (C=2C=CN=C (C2) S (=O) (=O) C) CC1) C3=CN=CC4=C3C=NN4C5=CC=C (F) C=C5
Molecular Formula
C22H18FN5O3S
Molecular Weight
451.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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