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BI 639667

BI 639667 is a potent and selective azaindazole-based CCR1 inhibitor, exhibiting an IC50 of 1.8 nM in calcium mobilization assays. This small molecule is a valuable research tool for investigating CCR1-mediated pathways in inflammatory and autoimmune diseases, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1295298-26-8

Product Name Alternative

CCR1 antagonist 8, CCR1, CCR-1 antagonist 8, CCR1 antagonist8, BI639667

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

99.86% (May vary between batches)

Solubility

DMSO:8 mg/mL (17.72 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.11 mM)

Smiles

O=C (NC1 (C=2C=CN=C (C2) S (=O) (=O) C) CC1) C3=CN=CC4=C3C=NN4C5=CC=C (F) C=C5

Molecular Formula

C22H18FN5O3S

Molecular Weight

451.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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