Cenisertib
Cenisertib is a potent ATP-competitive multi-kinase inhibitor targeting Aurora kinases, ABL1, AKT, STAT5, and FLT3. It suppresses tumor mast cell growth in vitro and demonstrates broad anti-tumor activity in xenograft models of pancreatic, breast, colon, ovarian, and lung cancers as well as leukemia.
Product Specifications
CAS Number
871357-89-0
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
[H][C@@]12C[C@@] ([H]) (C=C1) [C@@H] ([C@@H]2Nc1nc (Nc2ccc (N3CCN (C) CC3) c (C) c2) ncc1F) C (N) =O
Molecular Formula
C24H30FN7O
Molecular Weight
451.54
Storage Conditions
-20°C
Notes
For research use only.
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