GR 113808
GR 113808 is a selective 5-HT4 receptor antagonist with additional inhibitory activity at 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors. It is a valuable pharmacological tool used in neuroscience research to study serotonin receptor function and its modulation of dopaminergic pathways, as demonstrated by its ability to attenuate morphine-induced dopamine release in rat striatum.
Product Specifications
CAS Number
144625-51-4
Product Name Alternative
5-HT4 Receptor, 5-HT3 Receptor, 5-HT4, 5HTReceptor, 5-HT1A Receptor, 5-HT1, 5HT Receptor, 5-HT2, 5-HT2A Receptor, 5-HT3, 5-HT2C Receptor, GR113808, GR-113808, GR 113808
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.16% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (5.08 mM) ; DMSO:30 mg/mL (76.24 mM)
Smiles
Cn1cc (C (=O) OCC2CCN (CCNS (C) (=O) =O) CC2) c2ccccc12
Molecular Formula
C19H27N3O4S
Molecular Weight
393.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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