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GR 113808

GR 113808 is a selective 5-HT4 receptor antagonist with additional inhibitory activity at 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors. It is a valuable pharmacological tool used in neuroscience research to study serotonin receptor function and its modulation of dopaminergic pathways, as demonstrated by its ability to attenuate morphine-induced dopamine release in rat striatum.

Product Specifications

CAS Number

144625-51-4

Product Name Alternative

5-HT4 Receptor, 5-HT3 Receptor, 5-HT4, 5HTReceptor, 5-HT1A Receptor, 5-HT1, 5HT Receptor, 5-HT2, 5-HT2A Receptor, 5-HT3, 5-HT2C Receptor, GR113808, GR-113808, GR 113808

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.16% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (5.08 mM) ; DMSO:30 mg/mL (76.24 mM)

Smiles

Cn1cc (C (=O) OCC2CCN (CCNS (C) (=O) =O) CC2) c2ccccc12

Molecular Formula

C19H27N3O4S

Molecular Weight

393.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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