GSK864
GSK864 is a selective small molecule inhibitor targeting the cancer-associated IDH1 mutants R132C, R132H, and R132G. It is a valuable research tool for investigating the role of mutant IDH1 in oncology, particularly in studies of tumor metabolism, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1816331-66-4
Product Name Alternative
IDH1 mutants R132C, IDH1 mutants R132G, IDH1 mutants R132H, IDH1, GSK864, GSK-864, GSK 864
Field of Research
Metabolism Research
Purity
97.07% (May vary between batches)
Solubility
DMSO:100 mg/mL (179.02 mM) ; H2O:< 1 mg/mL (Insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.16 mM)
Smiles
COc1c (C) cc (NC (=O) c2nn (Cc3ccc (F) cc3) c3c2CN (C[C@]3 (C) C (N) =O) C (=O) c2ccc[nH]2) cc1C
Molecular Formula
C30H31FN6O4
Molecular Weight
558.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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