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GSK8814

GSK8814 is a potent and selective chemical probe targeting the ATAD2/ATAD2B bromodomains, with a pKd of 8.1 and over 500-fold selectivity versus BRD4 BD1. This inhibitor is a valuable tool for investigating the role of ATAD2 in oncology research, supporting both in vitro mechanistic studies and in vivo model validation.

Product Specifications

CAS Number

1997369-78-4

Field of Research

Epigenetics & Chromatin

Smiles

CO[C@H]1CNC[C@@H] (OCC2CCC (F) (F) CC2) [C@@H]1Nc1ncc (-c2cncc (C) c2) c2cc (C) c (=O) [nH]c12

Molecular Formula

C28H35F2N5O3

Molecular Weight

527.61

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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