Helenalin
Helenalin is an anti-inflammatory sesquiterpene lactone that selectively inhibits NF-κB by alkylating cysteine residues in the p65 subunit, blocking its DNA binding. This mechanism has been utilized in vitro to study inflammatory signaling pathways and has shown activity in cellular models of inflammation.
Product Specifications
CAS Number
6754-13-8
Field of Research
Signal Transduction
Purity
>98%
Bioactivity
NFkB inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml) .
Smiles
[H][C@@]12C[C@@H] (C) [C@]3 ([H]) C=CC (=O) [C@@]3 (C) [C@@H] (O) [C@]1 ([H]) C (=C) C (=O) O2
Molecular Formula
C15H18O4
Molecular Weight
262.31
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Natural sesquiterpenoid from Arnica species
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