HG6-64-1
HG6-64-1 (HMSL 10017-101-1) is a selective B-Raf V600E inhibitor, demonstrating potent activity with an IC50 of 90 nM in cellular assays. This compound is a valuable chemical probe for investigating MAPK/ERK pathway signaling in cancer research, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1315329-43-1
Product Name Alternative
HMSL 10017-101-1, HG6 64 1, HG6641, HG-6-64-1, HG6-64-1, B-RafV600E
Field of Research
Signal Transduction
Purity
99.89% (May vary between batches)
Solubility
DMSO:40 mg/mL (69.25 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (4.33 mM)
Smiles
O (C) C1=C2C (=NC=C1/C=C/C3=CC (C (NC4=CC (C (F) (F) F) =C (CN5CCN (CC) CC5) C=C4) =O) =CC=C3C) NC=C2
Molecular Formula
C32H34F3N5O2
Molecular Weight
577.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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