JNJ-46778212
JNJ-46778212 (VU 0409551) is a potent and selective positive allosteric modulator of the mGlu5 receptor, exhibiting an EC50 of 260 nM. It is a valuable research tool for investigating the role of mGlu5 in neuropsychiatric disorders and has been utilized in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1363281-27-9
Product Name Alternative
VU0409551, VU-0409551, VU 0409551, mGlu5, JNJ 46778212, JNJ46778212, JNJ-46778212
Field of Research
Neuroscience
Purity
99.24% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.37 mM) ; DMSO:80 mg/mL (227.04 mM)
Smiles
Fc1ccc (cc1) C (=O) N1CCc2nc (COc3ccccc3) oc2C1
Molecular Formula
C20H17FN2O3
Molecular Weight
352.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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