KIRA-7
KIRA-7 is an imidazopyrazine small molecule that acts as an allosteric inhibitor of IRE1α RNase activity by binding its kinase domain (IC50: 110 nM) . It exhibits anti-fibrotic properties and is utilized in research exploring endoplasmic reticulum stress in models of fibrotic disease, both in vitro and in vivo.
Product Specifications
CAS Number
1937235-76-1
Field of Research
Cell Biology
Smiles
CC1 (CC1) c1nc (-c2ccc (NC (=O) Nc3cccc (F) c3) c3ccccc23) c2c (N) nccn12
Molecular Formula
C27H23FN6O
Molecular Weight
466.51
Storage Conditions
-20°C
Notes
For research use only.
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