KZR-504
KZR-504 is a potent and selective inhibitor of the immunoproteasome subunit LMP2, demonstrating significant selectivity over LMP7 (IC50 = 51 nM and 4.274 μM, respectively) . This compound is a valuable research tool for studying immunoproteasome function in autoimmune and inflammatory disease models, both in cellular and animal studies.
Product Specifications
CAS Number
1629052-78-3
Field of Research
Protein Biochemistry
Smiles
C[C@@]1 (CO1) C (=O) [C@H] (Cc1ccccc1) NC (=O) [C@H] (CO) NC (=O) c1cccc (=O) [nH]1
Molecular Formula
C21H23N3O6
Molecular Weight
413.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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