α-Lipoic Acid (Standard)
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5].
Product Specifications
CAS Number
[1077-28-7]
Product Name Alternative
Thioctic acid (Standard) ; (±) -α-Lipoic acid (Standard) ; DL-α-Lipoic acid (Standard)
UNSPSC
12352005
Hazard Statement
H302, H315, H317, H319, H411
Target
Apoptosis; Endogenous Metabolite; HIV; Mitochondrial Metabolism; NF-κB; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/α-lipoic-acid-standard.html
Purity
99.90
Smiles
O=C(O)CCCCC1SSCC1
Molecular Formula
C8H14O2S2
Molecular Weight
206.33
Precautions
H302, H315, H317, H319, H411
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Isoform
HIV-1; Human Endogenous Metabolite; NF-κB
Available Sizes
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