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α-Lipoic Acid (Standard)

α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5].

Product Specifications

CAS Number

[1077-28-7]

Product Name Alternative

Thioctic acid (Standard) ; (±) -α-Lipoic acid (Standard) ; DL-α-Lipoic acid (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H317, H319, H411

Target

Apoptosis; Endogenous Metabolite; HIV; Mitochondrial Metabolism; NF-κB; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/α-lipoic-acid-standard.html

Purity

99.90

Smiles

O=C(O)CCCCC1SSCC1

Molecular Formula

C8H14O2S2

Molecular Weight

206.33

Precautions

H302, H315, H317, H319, H411

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Isoform

HIV-1; Human Endogenous Metabolite; NF-κB

Available Sizes

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