L-798106
L-798106 (CM9) is a potent and selective EP3 receptor antagonist with additional activity against EP4, EP1, and EP2 receptors. It reduces pro-inflammatory cytokine levels in atherosclerosis models and inhibits PGE2-induced cough, making it a valuable tool for studying prostaglandin signaling in inflammation and respiratory research.
Product Specifications
CAS Number
244101-02-8
Product Name Alternative
L798106, L-798106, EP2, EP1/2 receptor, EP1, EP3, EP3 receptor, EP4 receptor, EP4, GW671021, GW-671021, GW 671021, L 798106, CM9, CM-9, CM 9, Prostaglandin Receptor, ProstaglandinReceptor
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.97% (May vary between batches)
Solubility
DMSO:5 mg/mL (9.32 mM)
Smiles
COc1ccc (Br) cc1S (=O) (=O) NC (=O) \C=C\c1ccccc1Cc1ccc2ccccc2c1
Molecular Formula
C27H22BrNO4S
Molecular Weight
536.44
Storage Conditions
-20°C
Notes
For research use only.
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