Larotaxel
Larotaxel (XRP9881) is a taxane-based anticancer agent that stabilizes microtubules, inducing apoptotic cell death. It crosses the blood-brain barrier and shows reduced susceptibility to P-glycoprotein efflux. This compound is utilized in preclinical research for studying breast and bladder cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
156294-36-9
Product Name Alternative
Larotaxel, Pgp, P-glycoprotein, XRP9881, XRP-9881, XRP 9881
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.22% (May vary between batches)
Solubility
DMSO:50 mg/mL (60.1 mM)
Smiles
[H][C@@]12C[C@@H]3C[C@@]33C (=O) [C@] ([H]) (OC (C) =O) C4=C (C) [C@@H] (C[C@@] (O) ([C@@H] (OC (=O) c5ccccc5) [C@]3 ([H]) [C@@]1 (CO2) OC (C) =O) C4 (C) C) OC (=O) [C@H] (O) [C@@H] (NC (=O) OC (C) (C) C) c1ccccc1
Molecular Formula
C45H53NO14
Molecular Weight
831.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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