LY377604
LY377604 is a selective β3-adrenergic receptor agonist (EC50 = 2.4 nM) with antagonistic activity at β1/β2 receptors. This pharmacological profile makes it a useful research compound for investigating metabolic diseases, such as obesity, in both cellular and animal models.
Product Specifications
CAS Number
204592-94-9
Product Name Alternative
β1-adrenergic receptor, β2-adrenergic receptor, β1-adrenergic receptor, β2-adrenergic receptor, β3-adrenergic receptor, LY 377604, LY377604, LY-377604, human β3-adrenergic receptor, AdrenergicReceptor, Adrenergic Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.27% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.29 mM) ; DMSO:80 mg/mL (152.49 mM)
Smiles
O (C[C@H] (CNC (CC1=CC=C (OC2=CC=C (C (N) =O) C=N2) C=C1) (C) C) O) C3=C4C=5C (NC4=CC=C3) =CC=CC5
Molecular Formula
C31H32N4O4
Molecular Weight
524.61
Storage Conditions
-20°C
Notes
For research use only.
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