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M-110

M-110 is a potent, ATP-competitive small-molecule inhibitor exhibiting high selectivity for PIM-3 kinase (IC50=47 nM) over PIM-1/2 (IC50=2.5 μM) . It demonstrates anti-proliferative activity in prostate cancer cell lines (IC50=0.6-0.9 μM), supporting its use in oncology research for studying PIM kinase signaling in vitro.

Product Specifications

CAS Number

1395048-49-3

Product Name Alternative

M110, M-110, M 110, Pim3

Field of Research

Epigenetics & Chromatin, Signal Transduction

Purity

98.30% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.48 mM) ; DMSO:50 mg/mL (112.12 mM)

Smiles

CC\C (=N/NC (=O) c1ccnc (NCCCN2CCOCC2) c1) c1ccc (Cl) cc1O

Molecular Formula

C22H28ClN5O3

Molecular Weight

445.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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