M-110
M-110 is a potent, ATP-competitive small-molecule inhibitor exhibiting high selectivity for PIM-3 kinase (IC50=47 nM) over PIM-1/2 (IC50=2.5 μM) . It demonstrates anti-proliferative activity in prostate cancer cell lines (IC50=0.6-0.9 μM), supporting its use in oncology research for studying PIM kinase signaling in vitro.
Product Specifications
CAS Number
1395048-49-3
Product Name Alternative
M110, M-110, M 110, Pim3
Field of Research
Epigenetics & Chromatin, Signal Transduction
Purity
98.30% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.48 mM) ; DMSO:50 mg/mL (112.12 mM)
Smiles
CC\C (=N/NC (=O) c1ccnc (NCCCN2CCOCC2) c1) c1ccc (Cl) cc1O
Molecular Formula
C22H28ClN5O3
Molecular Weight
445.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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