M-525
M-525 is a first-in-class, covalent inhibitor of the menin-MLL interaction with low nanomolar cellular potency. It demonstrates anti-leukemia activity by suppressing the growth and MLL-fusion-driven gene expression in MLL-rearranged leukemia cells in vitro.
Product Specifications
CAS Number
2173582-08-4
Field of Research
Epigenetics & Chromatin
Smiles
[C@@] (C#N) ([C@@]1 ([C@@H] (NC (OC) =O) CCC1) [H]) (C2=CC (F) =CC=C2) [C@H]3CCN (CC4CN (C4) C5=CC=C (S (=O) (=O) C6CN (C (/C=C/CN (C) C) =O) C6) C=C5) CC3
Molecular Formula
C39H51FN6O5S
Molecular Weight
734.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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