Pavinetant
Pavinetant (MLE-4901) is an orally bioavailable, selective neurokinin-3 receptor (NK3R) antagonist. It is a research tool for investigating the role of NK3R signaling in menopausal hot flashes and other neuroendocrine pathways, with utility in both in vitro binding assays and in vivo preclinical models.
Product Specifications
CAS Number
941690-55-7
Product Name Alternative
AZD4901, AZD-4901, AZD2624, AZD-2624, AZD 4901, AZD 2624, Pavinetant, Neurokininreceptor, Neurokinin receptor, MLE 4901, MLE4901, MLE-4901, NK3R, NK3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.60% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.44 mM) ; DMSO:80 mg/mL (174.08 mM)
Smiles
CC[C@H] (NC (=O) c1c (NS (C) (=O) =O) c (nc2ccccc12) -c1ccccc1) c1ccccc1
Molecular Formula
C26H25N3O3S
Molecular Weight
459.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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