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MMAF sodium

MMAF sodium is a potent tubulin polymerization inhibitor employed as the cytotoxic payload in antibody-drug conjugates (ADCs) like Vorsetuzumab mafodotin. Its application extends to preclinical in vitro and in vivo cancer research, where it is studied for its antitumor mechanisms and efficacy in targeted drug delivery models.

Product Specifications

CAS Number

1799706-65-2

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

[H][C@@]1 ([C@@H] ([C@H] (C (N[C@H] (C ([O-]) =O) Cc2ccccc2) =O) C) OC) CCCN1C (C[C@H] ([C@@H] (N (C ([C@H] (C (C) C) NC ([C@H] (C (C) C) NC) =O) =O) C) [C@H] (CC) C) OC) =O.[Na+]

Molecular Formula

C39H64N5NaO8

Molecular Weight

753.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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