MMAF sodium
MMAF sodium is a potent tubulin polymerization inhibitor employed as the cytotoxic payload in antibody-drug conjugates (ADCs) like Vorsetuzumab mafodotin. Its application extends to preclinical in vitro and in vivo cancer research, where it is studied for its antitumor mechanisms and efficacy in targeted drug delivery models.
Product Specifications
CAS Number
1799706-65-2
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
[H][C@@]1 ([C@@H] ([C@H] (C (N[C@H] (C ([O-]) =O) Cc2ccccc2) =O) C) OC) CCCN1C (C[C@H] ([C@@H] (N (C ([C@H] (C (C) C) NC ([C@H] (C (C) C) NC) =O) =O) C) [C@H] (CC) C) OC) =O.[Na+]
Molecular Formula
C39H64N5NaO8
Molecular Weight
753.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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