Imofinostat
Imofinostat (MPT0E028) is an orally bioavailable pan-HDAC inhibitor, showing potent activity against HDAC1, HDAC2, and HDAC6. It exhibits anticancer effects in B-cell lymphoma and other tumors by inducing cell cycle arrest, apoptosis, and inhibiting Akt signaling in vitro and in vivo.
Product Specifications
CAS Number
1338320-94-7
Product Name Alternative
Akt, ABT301, ABT-301, MPT0E 028, MPT0E028, MPT-0E028, MPT0E-028, HDAC6, HDAC8, HDAC1, HDAC2, TMUC0012, TMU-C-0012
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Purity
99.24% (May vary between batches)
Solubility
DMSO:80 mg/mL (232.3 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (9.58 mM)
Smiles
ONC (=O) \C=C\c1ccc2N (CCc2c1) S (=O) (=O) c1ccccc1
Molecular Formula
C17H16N2O4S
Molecular Weight
344.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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