MRT00033659
MRT00033659 is a pyrazolo-pyridine analogue functioning as a potent, broad-spectrum kinase inhibitor, notably targeting CK1δ (IC50=0.9 μM) and CHK1 (IC50=0.23 μM) . Its mechanism induces p53 pathway activation and E2F-1 destabilization, supporting its application in cancer research for in vitro studies of cell cycle regulation and DNA damage response pathways.
Product Specifications
CAS Number
1401731-54-1
Field of Research
Cell Biology, Metabolism Research, Stem Cell & Developmental Biology
Smiles
CC (=O) Nc1cccc (c1) -c1cnc2[nH]nc (C) c2c1
Molecular Formula
C15H14N4O
Molecular Weight
266.3
Storage Conditions
-20°C
Notes
For research use only.
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