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MRT00033659

MRT00033659 is a pyrazolo-pyridine analogue functioning as a potent, broad-spectrum kinase inhibitor, notably targeting CK1δ (IC50=0.9 μM) and CHK1 (IC50=0.23 μM) . Its mechanism induces p53 pathway activation and E2F-1 destabilization, supporting its application in cancer research for in vitro studies of cell cycle regulation and DNA damage response pathways.

Product Specifications

CAS Number

1401731-54-1

Field of Research

Cell Biology, Metabolism Research, Stem Cell & Developmental Biology

Smiles

CC (=O) Nc1cccc (c1) -c1cnc2[nH]nc (C) c2c1

Molecular Formula

C15H14N4O

Molecular Weight

266.3

Storage Conditions

-20°C

Notes

For research use only.

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