MS-444
MS-444 (BE-34776) is a dual inhibitor of smooth muscle myosin light chain kinase (MLCK) and the RNA-binding protein HuR. It exhibits antitumor activity in preclinical models, including triple-negative breast cancer and colorectal cancer, and is used in research to study post-transcriptional gene regulation and cancer cell proliferation in vitro.
Product Specifications
CAS Number
150045-18-4
Product Name Alternative
BE34776, BE-34776, BE 34776, myosin, Myosin, MS 444, MS444, MS-444, MLCK, Serine kinase, threoninkinase, threonin kinase, Serinekinase
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
99.45% (May vary between batches)
Solubility
DMSO:40 mg/mL (173.75 mM)
Smiles
O=C1C=2C (O) =CC=C (O) C2CC3=COC (=C13) C
Molecular Formula
C13H10O4
Molecular Weight
230.22
Storage Conditions
-20°C
Notes
For research use only.
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