NF157
NF157 is a potent and selective P2Y11 receptor antagonist (pKi: 7.35) that reduces the expression of MMP-3 and MMP-13. This activity suggests its utility as a research tool for investigating osteoarthritis pathology and potential therapeutic strategies in relevant cellular and animal models.
Product Specifications
CAS Number
104869-26-3
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Smiles
[Na].[Na].[Na].[Na].[Na].[Na].OS (=O) (=O) c1cc (c2c (NC (=O) c3ccc (F) c (NC (=O) c4cccc (NC (=O) Nc5cccc (c5) C (=O) Nc5cc (ccc5F) C (=O) Nc5ccc (c6cc (cc (c56) S (O) (=O) =O) S (O) (=O) =O) S (O) (=O) =O) c4) c3) ccc (c2c1) S (O) (=O) =O) S (O) (=O) =O
Molecular Formula
C49H28F2N6Na6O23S6
Molecular Weight
1437.1
Storage Conditions
-20°C
Notes
For research use only.
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