NKY-80
NKY80 is a selective, non-competitive inhibitor of adenylyl cyclase, with highest potency against the type V isoform (IC50 = 8.3 μM) . This small molecule is a valuable research tool for investigating cAMP signaling pathways in cardiovascular and pulmonary research, applicable in both in vitro and ex vivo tissue studies.
Product Specifications
CAS Number
299442-43-6
Product Name Alternative
AC type II, AC type III, AC type V, Adenylyl cyclase, Adenylyl cyclase (AC), Adenylylcyclase, Adenylyl cyclase type V Inhibitor, NKY 80, NKY80, NKY-80
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
Adenylate cyclase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming) .
Smiles
NC1=NC2=C (C=N1) C (=O) CC (C2) C1=CC=CO1
Molecular Formula
C12H11N3O2
Molecular Weight
229.24
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Amino-7- (2-furanyl) -7,8-dihydro-5 (6H) -quainazolinone
Available Sizes
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