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Infigratinib phosphate

Infigratinib phosphate is a potent and selective small-molecule inhibitor of fibroblast growth factor receptors (FGFRs), demonstrating low nanomolar IC50 values against FGFR1-3. It is widely used in preclinical research to investigate FGFR-driven signaling in vitro and has shown antitumor efficacy in vivo models of various cancers.

Product Specifications

CAS Number

1310746-10-1

Product Name Alternative

NVP-BGJ 398 Phosphate, NVP-BGJ398 Phosphate, NVP-BGJ398 phosphate, NVP-BGJ-398 Phosphate, Infigratinib Phosphate, FGFR2, FGFR1, FGFR3, FGFR4, BGJ 398 Phosphate, BGJ398 Phosphate, BGJ-398 Phosphate, BGJ-398 phosphate

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.24% (May vary between batches)

Solubility

DMSO:11.7 mg/mL (17.77 mM)

Smiles

O=C (NC=1C (Cl) =C (OC) C=C (OC) C1Cl) N (C=2N=CN=C (C2) NC3=CC=C (C=C3) N4CCN (CC) CC4) C.O=P (O) (O) O

Molecular Formula

C26H34Cl2N7O7P

Molecular Weight

658.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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