Infigratinib phosphate
Infigratinib phosphate is a potent and selective small-molecule inhibitor of fibroblast growth factor receptors (FGFRs), demonstrating low nanomolar IC50 values against FGFR1-3. It is widely used in preclinical research to investigate FGFR-driven signaling in vitro and has shown antitumor efficacy in vivo models of various cancers.
Product Specifications
CAS Number
1310746-10-1
Product Name Alternative
NVP-BGJ 398 Phosphate, NVP-BGJ398 Phosphate, NVP-BGJ398 phosphate, NVP-BGJ-398 Phosphate, Infigratinib Phosphate, FGFR2, FGFR1, FGFR3, FGFR4, BGJ 398 Phosphate, BGJ398 Phosphate, BGJ-398 Phosphate, BGJ-398 phosphate
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.24% (May vary between batches)
Solubility
DMSO:11.7 mg/mL (17.77 mM)
Smiles
O=C (NC=1C (Cl) =C (OC) C=C (OC) C1Cl) N (C=2N=CN=C (C2) NC3=CC=C (C=C3) N4CCN (CC) CC4) C.O=P (O) (O) O
Molecular Formula
C26H34Cl2N7O7P
Molecular Weight
658.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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