Buparlisib Hydrochloride
Buparlisib hydrochloride (BKM120 HCl) is an orally active, pan-class I PI3K inhibitor that acts at nanomolar concentrations. It is widely used in preclinical research to study PI3K pathway dysregulation in various cancers, including breast cancer and glioblastoma, through both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1312445-63-8
Product Name Alternative
Buparlisib Hydrochloride, BKM-120 Hydrochloride, BKM 120 Hydrochloride, BKM120 Hydrochloride, NVP-BKM 120 Hydrochloride, NVP-BKM120 Hydrochloride, NVP-BKM-120 Hydrochloride, p110α, p110γ, p110δ, p110β, p110α-E545K, p110α-H1047R, mTOR, Vps34
Field of Research
Cell Biology, Signal Transduction
Purity
98.94% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.48 mM) ; DMSO:≥ 40 mg/mL
Smiles
Cl.FC (F) (F) C1=CC (=NC=C1C=2N=C (N=C (C2) N3CCOCC3) N4CCOCC4) N
Molecular Formula
C18H22ClF3N6O2
Molecular Weight
446.85
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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