Oglemilast
Oglemilast (GRC 3886) is a potent and orally bioavailable PDE4 inhibitor, with an IC50 of 0.5 nM for PDE4D3. It reduces pulmonary eosinophil and neutrophil infiltration in experimental models, supporting its research application for inflammatory airway diseases like asthma and COPD.
Product Specifications
CAS Number
778576-62-8
Product Name Alternative
PDE4D3, PDE4D, Oglemilast, GRC-3886, GRC 3886, GRC3886
Field of Research
Metabolism Research
Purity
98.11% (May vary between batches)
Solubility
DMSO:3.6 mg/mL (6.97 mM)
Smiles
CS (=O) (=O) Nc1ccc2oc3c (OC (F) F) ccc (C (=O) Nc4c (Cl) cncc4Cl) c3c2c1
Molecular Formula
C20H13Cl2F2N3O5S
Molecular Weight
516.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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