PAT-048
PAT-048 is a potent and selective autotaxin inhibitor (IC50=20 nM) shown to reduce dermal fibrosis in vivo and suppress IL-6 mRNA. It is a valuable research tool for studying lysophosphatidic acid (LPA) signaling in fibrotic diseases, including skin and lung fibrosis models.
Product Specifications
CAS Number
1359983-15-5
Field of Research
Metabolism Research
Smiles
CC=1N (C=2C (C1SC3=C (F) C (C (O) =O) =CC=C3) =CC=C (Cl) C2F) C4=CN (CCC) N=C4
Molecular Formula
C22H18ClF2N3O2S
Molecular Weight
461.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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