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PBOX 6

PBOX 6 is a pyrrolo-1,5-benzoxazepine compound exhibiting anticancer activity. It inhibits breast cancer cell proliferation in vitro and induces apoptosis in leukemia cells by JNK-mediated phosphorylation and inactivation of Bcl-2/Bcl-XL. Its research applications include studying apoptosis mechanisms and oncogenic signaling pathways in various cancer models.

Product Specifications

CAS Number

290814-68-5

Product Name Alternative

Apoptosis, PBOX 6, PBOX6, PBOX-6

Field of Research

Cell Biology, Signal Transduction

Purity

98.18% (May vary between batches)

Solubility

DMSO:30 mg/mL (75.67 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (5.04 mM)

Smiles

CN (C) C (=O) OC1=C (Oc2ccccc2-n2cccc12) c1cccc2ccccc12

Molecular Formula

C25H20N2O3

Molecular Weight

396.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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