PD-118057
PD-118057 is a potent activator of the hERG potassium channel, enhancing its current to reduce cellular excitability. It is a research tool for studying cardiac electrophysiology, particularly in models of long QT syndrome and heart failure, with applications in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
313674-97-4
Product Name Alternative
Gardos channel, Human ether-a-go-go-related gene channel, hERG, PD 118057, PD118057, PD-118057, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
98.97% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (8.54 mM) ; DMSO:90 mg/mL (233 mM)
Smiles
OC (=O) c1ccccc1Nc1ccc (CCc2ccc (Cl) c (Cl) c2) cc1
Molecular Formula
C21H17Cl2NO2
Molecular Weight
386.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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