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PD-118057

PD-118057 is a potent activator of the hERG potassium channel, enhancing its current to reduce cellular excitability. It is a research tool for studying cardiac electrophysiology, particularly in models of long QT syndrome and heart failure, with applications in both in vitro and in vivo experimental settings.

Product Specifications

CAS Number

313674-97-4

Product Name Alternative

Gardos channel, Human ether-a-go-go-related gene channel, hERG, PD 118057, PD118057, PD-118057, Potassium Channel, PotassiumChannel

Field of Research

Pharmacology & Drug Discovery

Purity

98.97% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (8.54 mM) ; DMSO:90 mg/mL (233 mM)

Smiles

OC (=O) c1ccccc1Nc1ccc (CCc2ccc (Cl) c (Cl) c2) cc1

Molecular Formula

C21H17Cl2NO2

Molecular Weight

386.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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