Petesicatib
Petesicatib (RG 7625) is a selective cathepsin S (Cat-S) inhibitor used in research for autoimmune conditions like primary Sjögren's syndrome. It is employed in both in vitro and in vivo studies to investigate the role of Cat-S in antigen presentation and immune modulation.
Product Specifications
CAS Number
1252637-35-6
Product Name Alternative
CysteineProtease, Cysteine Protease, Cathepsin S, RO 5459072, RO-5459072, RG-7625, RG 7625, Petesicatib
Field of Research
Protein Biochemistry
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.63 mM) ; DMSO:100 mg/mL (165.69 mM)
Smiles
Cn1cc (cn1) -c1ccc (c (c1) C (F) (F) F) S (=O) (=O) [C@@H]1C[C@H] (N (C1) C (=O) C1 (CC1) C (F) (F) F) C (=O) NC1 (CC1) C#N
Molecular Formula
C25H23F6N5O4S
Molecular Weight
603.54
Storage Conditions
-20°C
Notes
For research use only.
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