Rociletinib hydrobromide
Rociletinib hydrobromide is an oral kinase inhibitor that selectively targets EGFR L858R/T790M mutant (Ki 21.5 nM) over wild-type EGFR (Ki 303.3 nM) . It is a research tool for investigating resistance mechanisms in non-small cell lung cancer, applicable in both in vitro biochemical assays and in vivo xenograft models.
Product Specifications
CAS Number
1446700-26-0
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
Br.COc1cc (ccc1Nc1ncc (c (Nc2cccc (NC (=O) C=C) c2) n1) C (F) (F) F) N1CCN (CC1) C (C) =O
Molecular Formula
C27H29BrF3N7O3
Molecular Weight
636.46
Storage Conditions
-20°C
Notes
For research use only.
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