Conteltinib

Conteltinib (CT-707) is a multi-target kinase inhibitor active against FAK, ALK, and Pyk2. It demonstrates antitumor efficacy in research models of ALK-positive NSCLC and hepatocellular carcinoma, where it overcomes sorafenib resistance by inhibiting YAP signaling under hypoxic conditions.

Product Specifications

CAS Number

1384860-29-0

Product Name Alternative

ALK, Conteltinib, CT 707, CT707, CT-707, FAK, SY-707, PYK2

Field of Research

Cardiovascular Research, Signal Transduction

Purity

98.12% (May vary between batches)

Solubility

DMSO:20 mg/mL (31.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.15 mM)

Smiles

COc1cc (ccc1Nc1nc2NCCc2c (Nc2ccccc2S (=O) (=O) NC (C) C) n1) N1CCC (CC1) N1CCN (C) CC1

Molecular Formula

C32H45N9O3S

Molecular Weight

635.82

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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