Conteltinib
Conteltinib (CT-707) is a multi-target kinase inhibitor active against FAK, ALK, and Pyk2. It demonstrates antitumor efficacy in research models of ALK-positive NSCLC and hepatocellular carcinoma, where it overcomes sorafenib resistance by inhibiting YAP signaling under hypoxic conditions.
Product Specifications
CAS Number
1384860-29-0
Product Name Alternative
ALK, Conteltinib, CT 707, CT707, CT-707, FAK, SY-707, PYK2
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.12% (May vary between batches)
Solubility
DMSO:20 mg/mL (31.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.15 mM)
Smiles
COc1cc (ccc1Nc1nc2NCCc2c (Nc2ccccc2S (=O) (=O) NC (C) C) n1) N1CCC (CC1) N1CCN (C) CC1
Molecular Formula
C32H45N9O3S
Molecular Weight
635.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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