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Dirlotapide

Dirlotapide (CP742033) is a selective intestinal MTP inhibitor that reduces body weight in diabetic dogs by dose-dependently decreasing food intake, potentially via enhanced peptide YY release. It is used in obesity research, with studies demonstrating its effects in both in vivo canine models and in vitro assays investigating lipid metabolism.

Product Specifications

CAS Number

481658-94-0

Product Name Alternative

MTP, CP 742033, CP742033, CP-742033, Dirlotapide, Slentrol

Field of Research

Metabolism Research, Protein Biochemistry

Purity

98.47% (May vary between batches)

Solubility

DMSO:262.5 mg/mL (389.06 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CN (Cc1ccccc1) C (=O) [C@@H] (NC (=O) c1cc2cc (NC (=O) c3ccccc3-c3ccc (cc3) C (F) (F) F) ccc2n1C) c1ccccc1

Molecular Formula

C40H33F3N4O3

Molecular Weight

674.71

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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